Real-world treatment patterns and survival outcomes in men with metastatic castration-resistant prostate cancer in Finland: a national, population-based cohort study
Rannikko A, Hölsä O, Ågesen T, Ekman M, Mattila R. Acta Oncologica (2025). DOI: 10.2340/1651-226X.2025.42173
https://doi.org/10.2340/1651-226X.2025.42173
Predictors of revision endoscopic sinus surgery in Finnish patients with chronic rhinosinusitis with nasal polyps
Toppila-Salmi S, Lyly A, Simin J, Aakko J, Haugom Olsen H, Lehtimäki L. Clinical and Translational Allergy (2025). DOI: 10.1002/clt2.70032
https://doi.org/10.1002/clt2.70032
Increasing incidence and prevalence of Hodgkin’s lymphoma in Finland: a population-based registry study
Antikainen T, Hannuksela N, Anttalainen A, Partanen A, Rönkä A, Kuitunen H, Ukkola-Vuoti L, Toppila I, Miettinen T, Kuittinen O. European Journal of Public Health (2025). DOI: 10.1093/eurpub/ckaf002
https://doi.org/10.1093/eurpub/ckaf002
A real-world study on the impact of infection load on mortality in multiple myeloma patients in Finland
Anttalainen A, Havula E, Kysenius K, Toppila I, Miettinen T, Lassenius MI, Silvennoinen R, Partanen A, Putkonen M. Annals of Hematology (2024). DOI: 10.1007/s00277-024-06101-3
https://pubmed.ncbi.nlm.nih.gov/39676133
Real-world results of first-line immunotherapy or targeted therapy for metastatic melanoma in Finland: a cohort study
Mattila K, Tiainen L, Vikkula J, Kreutzman A, Engström M, Kysenius K, Hölsä O, Hernesniemi S, Hemmilä P, Pystynen A, Mäkelä S. Future Oncology (2024). DOI: 10.1080/14796694.2024.2403329
https://doi.org/10.1080/14796694.2024.2403329
Characteristics, treatment and disease burden among stage 3-4 chronic kidney disease patients with and without type 2 diabetes in Finland during 2016-2022
Metsärinne K, Bodegård J, Toppila I, Uusi-Rauva K, Elmerdahl Frederiksen L, Brinkmann S. NDT (2024). DOI: 10.1093/ndt/gfae242
https://pubmed.ncbi.nlm.nih.gov/39510970
Prevalence, prognosis, and health care resource utilization in carriers of pathogenic germline variants in BRCA1/2 with incident early-stage breast cancer: a Finnish population-based study
Karihtala P, Laatikainen O, Tuominen S, Ågesen T, Eliasen R. Acta Oncologica (2024). DOI: 10.2340/1651-226X.2024.40829
https://pubmed.ncbi.nlm.nih.gov/39319938
Attribution of smoking to healthcare costs in the postoperative interval
Gräsbeck H, Reito A, Ekroos H, Aakko J, Hölsä O, Vasankari T. BJS Open (2024). DOI: 10.1093/bjsopen/zrae090
https://doi.org/10.1093/bjsopen/zrae090
Comorbidities and survival of multiple myeloma patients diagnosed in Finland between 2000 and 2021
Kysenius K, Anttalainen A, Toppila I, Miettinen T, Lassenius MI, Lievonen J, Partanen A, Silvennoinen R, Putkonen M. Annals of Hematology (2024). DOI: 10.1007/s00277-024-05865-y
https://doi.org/10.1007/s00277-024-05865-y
Survival of patients with classical Hodgkin lymphoma in Finland: a national population-based analysis
Hannuksela N, Partanen A, Anttalainen A, Ukkola-Vuoti L, Toppila I, Vikkula J, Marin K, Kuitunen H, Miettinen T, Kuittinen O, Rönkä A. Blood Cancer Journal (2024). DOI: 10.1038/s41408-024-01125-4
https://doi.org/10.1038/s41408-024-01125-4
Healthcare Resource Utilisation of Severe Uncontrolled T2low and Non-T2low Asthma in Finland During 2018-2021
Persson J, Aakko J, Kaijala S, Lassenius MI, Viinanen A, Kankaanranta H, Lehtimäki L. Journal of Asthma and Allergy (2024). DOI: 10.2147/JAA.S455911
https://pubmed.ncbi.nlm.nih.gov/39050030
Treatment and clinical outcomes of patients with acute myeloid leukemia in Finland 2010-2020: A retrospective analysis of electronic health records
Ranti J, Pudas H, Ranta M, Tuominen S, Uusi-Rauva K, Lammela J. European Journal of Haematology (2024) DOI: 10.1111/ejh.14272
https://doi.org/10.1111/ejh.14272
Real-World Evidence Study of Patients with KRAS-Mutated NSCLC in Finland
Anttalainen A, Pietarinen P, Tuominen S, Mattila R, Mutka A, Aija Knuuttila. Current Oncology (2024). DOI: 10.3390/curroncol31050205
https://www.mdpi.com/1718-7729/31/5/205
Trends in clinical characteristics, medication use, and glycemic control in insulin-treated patients with type 1and type 2 diabetes in Finland in 2012–2019: Nationwide real-world evidence study
Niskanen L, Hannula M, Kysenius K, Kaijala S, Lassenius MI, Valle TT. Journal of Diabetes (2024). DOI: 10.1111/1753-0407.13491
https://pubmed.ncbi.nlm.nih.gov/38273701/
Expenditure and survival of adult patients with intestinal failure due to short bowel syndrome: real-world evidence from Southern Finland
Ukkola-Vuoti L, Tuominen S, Pohju A, Kovac B, Lassenius MI, Merras-Salmio L, Pakarinen MP, Sallinen V, Pikkarainen S. Scand J Gastroenterology (2024). DOI: 10.1080/00365521.2024.2303063
https://pubmed.ncbi.nlm.nih.gov/38217349
Tofacitinib real-world experience in ulcerative colitis in Finland (FinTofUC): a retrospective non-interventional multicenter patient chart data study
Molander P, Kosunen M, Eronen H, Tillonen J, Käräjämäki A, Heikkinen M, Punkkinen J, Mattila R, Toppila I, Hölsä O, Kalpala K, Henrohn D, Af Björkesten CG. Scand J Gastroenterology (2024). DOI: 10.1080/00365521.2023.2298361
https://pubmed.ncbi.nlm.nih.gov/38156792
Cyclosporine vs. tacrolimus after liver transplantation for primary sclerosing cholangitis – a propensity score-matched intention-to-treat analysis
Åberg F, Sallinen V, Tuominen S, Adam R, Karam V, Mirza D, Heneghan MA, Line P-D, Bennet W, Ericzon B-G, Grat, M, Lodge P, Rasmussen A, Schmelzle M, Thorburn D, Fondevila C, Helanterä I, Nordin, A. Journal of Hepatology (2023). DOI: 10.1016/j.jhep.2023.08.031
https://www.journal-of-hepatology.eu/article/S0168-8278(23)05100-0/fulltext
Observational study on the evolution of systemic treatments for advanced renal cell carcinoma in Southwest Finland between 2010 and 2021
Hölsä O, Teittinen K, Anttalainen A, Ukkola-Vuoti L, Summanen M, Mattila KE. Therapeutic advances in urology (2023). DOI: 10.1177/17562872231206243
https://pubmed.ncbi.nlm.nih.gov/37941979
Real-world treatment patterns of Finnish adult patients with atopic dermatitis: From topicals to systemic therapy
Kiiski V, Vikkula J, Ukkola-Vuoti L, Lassenius MI, Kopra J. JEADV Clinical Practice (2023).
DOI: 10.1002/jvc2.247
https://doi.org/10.1002/jvc2.247
Real-world evidence on multiple myeloma treated in 2013-2019 in the Hospital District of Helsinki and Uusimaa, Finland
Johanna Vikkula, Kristiina Uusi-Rauva, Tuuli Ranki, Iiro Toppila, Maria Aalto-Setälä, Katariina Pousar, Lotta Vassilev, Kimmo Porkka, Raija Silvennoinen, Oscar Brück. Future Oncology (2023). DOI: 10.2217/fon-2023-0120
https://pubmed.ncbi.nlm.nih.gov/37828901
Use of Linked Nordic Registries for Population Studies in Hematologic Cancers:
The Case of Multiple Myeloma
Abildgaard N, Freilich J, Anttila P, Bent-Ennakhil N, Ma Y, Lassenius M, Ørstavik S, Toppila I, Waage A, Turesson I, Hansson M. Clinical Epidemiology (2023). DOI: 10.2147/CLEP.S413587
https://doi.org/10.2147/CLEP.S413587
Pediatric short bowel syndrome: real-world evidence on incidence and hospital resource use from a Finnish data lake
Puttonen M, Tuominen S, Ukkola-Vuoti L, Lassenius MI, Virtanen H, Merras-Salmio L, Pakarinen M. Journal of Pediatric Gastroenterology and Nutrition (2023). DOI: 10.1097/MPG.0000000000003894
https://doi.org/10.1097/MPG.0000000000003894
The Burden of Genital Warts in Finland: Cross-Sectional Analysis of the Prevalence and Direct Medical Costs in 2018
Gylling A, Uusi-Rauva K, Toppila I, Hiltunen-Back E. Vaccines (2023). DOI: 10.3390/vaccines11071202
https://doi.org/10.3390/vaccines11071202
Type 2 Low Biomarker Stability and Exacerbations in Severe Uncontrolled Asthma
Viinanen A, Aakko J, Lassenius MI, Telg G, Nieminen K, Kaijala S, Lehtimäki L, Kankaanranta H. Biomolecules (2023). DOI: 10.3390/biom13071118
https://www.mdpi.com/2218-273X/13/7/1118#
Smoking is a predictor of complications in all types of surgery: a machine learning-based big data study
Gräsbeck H, Reito A, Ekroos H, Aakko J, Hölsä O, Vasankari T. BJS Open (2023). DOI: 10.1093/bjsopen/zrad016
https://doi.org/10.1093/bjsopen/zrad016
Burden of idiopathic inflammatory rheumatic diseases in occupational healthcare: increased absenteeism and healthcare resource utilization
Ukkola-Vuoti L, Karlsson A, Tuominen S, Lassenius MI, Aaltonen J, Ranta M, Kosunen M, Renlund M, Lehtonen A, Puolakka K. Scan J Work Environ Health (2023). DOI: 10.5271/sjweh.4095
https://www.sjweh.fi/article/4095
Sydämen vajaatoiminnan ilmaantuvuus ja hoidon kustannukset Suomessa vuosina 2012-2019
Ukkola-Vuoti L, Toppila I, Säävuori N, Kirjavainen A, Ukkonen H, Pentikäinen M. Duodecim (2023) 2023;139(6):455-62.
https://www.duodecimlehti.fi/lehti/2023/6/duo17603
Effect of Disease Severity on Comorbid Conditions in Atopic Dermatitis: Nationwide Registry-Based Investigation in Finnish Adults
Kiiski V , Ukkola-Vuoti L, Vikkula J, Ranta M, Lassenius MI, Kopra J.
Acta Dermato-Venereologica (2023) Volume 103. DOI: 10.2340/actadv.v103.4447
https://doi.org/10.2340/actadv.v103.4447
The burden of chronic rhinosinusitis with nasal polyps and its relation to asthma in Finland
Toppila-Salmi S, Hällfors J, Aakko J, Mannerström B, Nieminen K, Telg G, Lehtimäki L. Clinical and Translational Allergy (2022) Volume 12, Issue 10. DOI: 10.1002/clt2.12200
https://doi.org/10.1002/clt2.12200
Comorbidity characteristics of multiple myeloma patients diagnosed in Finland 2005-2016
Toppila I, Kysenius K, Miettinen T, Lassenius MI, Lievonen J, Anttila P. Annals of Hematology (2022) DOI: 10.1007/s00277-022-04959-9
https://doi.org/10.1007/s00277-022-04959-9
Screening for potential undiagnosed Gaucher disease patients: Utilisation of the Gaucher earlier diagnosis consensus point-scoring system (GED-C PSS) in conjunction with electronic health record data, tissue specimens, and small nucleotide polymorphism (SNP) genotype data available in Finnish biobanks
Pehrsson M, Heikkinen H, Wartivaara-Kautto U, Mäntylahti S, Bäckström P, Lassenius MI, Uusi-Rauva K, Carpén O, Elomaa K. Molecular Genetics and Metabolism Reports (2022) DOI: 10.1016/j.ymgmr.2022.100911
https://doi.org/10.1016/j.ymgmr.2022.100911
Cardiovascular outcome according to renal status in Finnish patients with type 2 diabetes
Hellman TA, Skare O-L, Lee C, Wagner U, Vikkula J, Hällfors J, Laatikainen O, Lassenius MI, Metsärinne K. Diabetes Epidemiology and Management (2022) DOI: 10.1016/j.deman.2022.100103
https://doi.org/10.1016/j.deman.2022.100103
Retrospective, Registry-based, Cohort Investigation of Clinical Outcomes in Patients with Cutaneous Squamous Cell Carcinoma and Basal Cell Carcinoma in Finland
Tuominen S, Ukkola-Vuoti L, Riihilä P, Knuutila JS, Kähäri VM, Lassenius M, Ranki T, Pousar K, Vassilev L, Vuoti S, Mattila K. Acta Derm Venereol (2022) DOI: 10.2340/actadv.v102.2073. PMID: 35356995.
https://medicaljournalssweden.se/actadv/article/view/2073
Cardiovascular event rate and death in high-risk secondary prevention patient cohort in Finland: A registry study
Toppila I, Ukkola-Vuoti L, Perttilä J, Törnwall O, Sinisalo J, Hartikainen J, Lehto S. Clinical Cardiology (2022) DOI: 10.1002/clc.23814.
https://pubmed.ncbi.nlm.nih.gov/35289408/
Real-world data on diffuse large B-cell lymphoma in 2010-2019: usability of large data sets of Finnish hospital data lakes
Tuominen S, Uusi-Rauva K, Blom T, Jyrkkiö S, Tuppurainen K, Alanne E. Future Oncology. 2022 Mar;18(9):1103-1114. doi: 10.2217/fon-2021-0806. Epub 2022 Feb 3. PMID: 35109670.
https://www.futuremedicine.com/doi/10.2217/fon-2021-0806
Characteristics and survival trends in Finnish multiple myeloma patients – a nationwide real-world evidence study
Toppila I, Miettinen T, Lassenius MI, Lievonen J, Bauer M, Anttila P. Ann Hematol (2021). DOI: 10.1007/s00277-021-04481-4.
https://doi.org/10.1007/s00277-021-04481-4
The Gaucher earlier diagnosis consensus point-scoring system (GED-C PSS): Evaluation of a prototype in Finnish Gaucher disease patients and feasibility of screening retrospective electronic health record data for the recognition of potential undiagnosed patients in Finland
Savolainen MJ, Karlsson A, Rohkimainen S, Toppila I, Lassenius MI, Vaca Falconi C, Uusi-Rauva K ja Elomaa K. Molecular Genetics and Metabolism Reports (2021) DOI: 10.1016/j.ymgmr.2021.100725.
https://doi.org/10.1016/j.ymgmr.2021.100725
Recurrent hospitalizations are associated with increased mortality across the ejection fraction range in heart failure
Huusko J, Tuominen S, Studer R, Corda S, Proudfoot C, Lassenius MI ja Ukkonen H. ESC Heart Failure (2020) DOI: 10.1002/ehf2.12792.
https://onlinelibrary.wiley.com/doi/full/10.1002/ehf2.12792
Cardiovascular event rates increase after each recurrence and associate with poor statin adherence
Lassenius MI, Toppila I, Bergius S, Perttilä J, Airaksinen KEJ ja Pietilä M. European Journal of Preventive Cardiology (2020) DOI: 10.1177/2047487320904334.
https://doi.org/10.1177/2047487320904334
Forced Vital Capacity (FVC) decline, mortality and healthcare resource utilization in idiopathic pulmonary fibrosis
Lassenius MI, Toppila I, Pöntynen N, Kasslin L, Kaunisto J, Kilpeläinen M ja Laitinen T. European Clinical Respiratory Journal (2019) 7:1, 1702618, DOI: 10.1080/20018525.2019.1702618.
https://www.tandfonline.com/doi/full/10.1080/20018525.2019.1702618
The burden of adult asthma in Finland: impact of disease severity and eosinophil count on health care resource utilization
Viinanen A, Lassenius M, Toppila I, Karlsson A, Veijalainen L, Idänpään-Heikkilä J ja Laitinen T. Journal of Asthma (2019). DOI: 10.1080/02770903.2019.1633664.
https://www.tandfonline.com/doi/full/10.1080/02770903.2019.1633664
Heart failure in Finland: clinical characteristics, mortality, and healthcare resource use
Huusko J, Kurki S, Toppila I, Purmoen T, Lassenius M, Gullberg E, Bruce-Wirta S ja Ukkonen H. ESC Heart Failure (2019). DOI: 10.1002/ehf2.12443.
https://www.ncbi.nlm.nih.gov/pubmed/31054212
Burden of migraine in Finland: health care resource use, sick-leaves and comorbidities in occupational health care
Korolainen M, Kurki S, Lassenius M, Toppila I, Costa-Scharplatz M, Purmonen T ja Nissilä M. Journal of headache and pain (2019) 20:13. DOI: 10.1186/s10194-019-0964-5.
https://rdcu.be/bmtGA
Type 2 diabetes and treatment intensification in primary care in Finland
Niskanen L, Hahl J, Haukka J, Leppä E, Miettinen T, Mushnikov V, Sipilä R, Tamminen N, Vattulainen P ja Korhonen P. Acta Diabetologica (2018) 55:1171-1179.
https://www.ncbi.nlm.nih.gov/pubmed/30083982
Health care resource utilization and characteristics of patients with eosinophilic asthma in secondary health care in Finland
Mäkelä MJ, Christensen HN, Karlsson A, Rastogi S ja Kettunen K. European Clinical Respiratory Journal (2018) 5(1):1458560.
https://www.ncbi.nlm.nih.gov/pubmed/29696083
Re-treatment with varenicline is a cost-effective aid for smoking cessation
Kautiainen K, Ekroos H, Puhakka M, Liira H, Laine J, Linden K, Hahl J. J Med Econ. 2017 Mar;20(3):246-252. DOI: 10.1080/13696998.2016.1249485.
https://pubmed.ncbi.nlm.nih.gov/27754739/
Burden of illness in multiple sclerosis (DEFENSE) study: the costs and quality-of-life of Finnish patients with multiple sclerosis
Ruutiainen J, Viita A-M, Hahl J, Sundell J, Nissinen H. J Med Econ 2016;19(1):21-33. DOI: 10.3111/13696998.2015.1086362.
https://pubmed.ncbi.nlm.nih.gov/26360615/